Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes

Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes

It’s nicely established that plasmids play an vital function within the dissemination of antimicrobial resistance (AMR) genes; nevertheless, little is understood in regards to the function of the underlying interactions between totally different plasmid classes and different cell genetic components (MGEs) in shaping the promiscuous unfold of AMR genes. Right here, we developed a...